AOD-9604
Monograph · CAOD-9604
C-terminal hGH fragment (176-191). Originally developed as a fat-burning analog of growth hormone without GH's metabolic side effects.
How it clearsHalf cleared in ~30min. Most (~96%) gone by ~2.5h.
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This compound sits in research-grey territory. The caveats below carry more weight than for FDA-approved entries — read them.
Synthetic 16-amino acid sequence. Phase 2b trials in Australia (Metabolic Pharmaceuticals) for obesity failed primary endpoint. Often marketed as joint/cartilage adjunct based on limited preclinical data. TGA-listed in Australia for compounding; FDA does not recognize as a drug.
Experimental — the mechanism is plausible, but human validation at meaningful scale doesn't exist yet. Metabolic effects are particularly susceptible to confounding from diet, sleep, and stress. Run this only with a controlled baseline and isolate variables before drawing conclusions.
Failed phase 2b for primary obesity endpoint. Cartilage/joint claims rest on a few preclinical studies. Treat as speculative.
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- CLimited evidence
AOD-9604 fragment shows lipolytic activity in preclinical models
1 supporting referencesVerified 23d ago
External links to PubMed searches, ClinicalTrials.gov, and FDA materials. We do not host papers — we point at canonical sources.
Pre-filled with this compound's published dose range: 300-500 µg · daily, subcutaneous
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