Boron
Trace mineral. Modulates free + bioavailable testosterone via SHBG-binding effect (reduces sex-hormone-binding globulin in some studies → more free testosterone). Also affects bone metabolism + calcium handling.
How it clearsHalf cleared in ~21h. Most (~96%) gone by ~4d.
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Naghii 2011 + Pizzorno 2015 reviews aggregate the boron + testosterone evidence: short-term high-dose (10 mg/day) boron raises free testosterone ~28% and lowers SHBG ~9% in healthy adult men over 7 days. The androgenic-supplement community ran with this finding; effect size + duration on chronic supplementation are more modest than the acute-trial headline suggests. Also relevant for bone health + arthritis cohorts via calcium-metabolism pathways. RDA isn't set in the US; tolerable upper intake is 20 mg/day.
Real-world chronic-supplementation effect on testosterone is smaller than acute-trial headlines suggest. Estrogen-axis effect: same studies show small estradiol rises, which is relevant for estrogen-sensitive cohorts. Don't exceed 20 mg/day. Pharmacy quality varies — third-party tested brands.
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- BModerate evidence
Raises free testosterone + lowers SHBG in adult men via short-term high-dose supplementation.
1 supporting referencesVerified today - CLimited evidence
Supports bone health + reduces arthritis-symptom severity.
1 supporting referencesVerified today
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