Recombinant 191-amino acid human growth hormone. Direct GH receptor agonism — supraphysiologic doses drive IGF-1 elevation, lipolysis, and protein anabolism.
FDA-approved (Genotropin, Humatrope, Norditropin, etc.) for pediatric GH deficiency, adult GH deficiency, Turner syndrome, and several other defined indications. Off-label anti-aging / body-composition use is widespread in private clinics and grey-market sources. Sustained supraphysiologic IGF-1 elevation is a real risk factor for insulin resistance and certain cancers.
Off-label use without endocrinologist oversight skips required IGF-1, A1c, and cancer screening. Supraphysiologic dosing carries documented risks. Counterfeit HGH is endemic in grey market.
191 aa recombinant somatropin. Truncated rendering only — full chain too long for visual.
Stack doesn't rank peptides — we surface the diversity of opinion. Each card paraphrases a public-record stance from a named source. Where they conflict is where you should slow down and read both.
GH (somatropin) is FDA-approved across multiple brands (Genotropin, Humatrope, Norditropin, Omnitrope, Saizen) for adult and pediatric GH deficiency. Decades of efficacy + safety data. Cardiovascular outcomes are cleaner than IGF-1 alone. Off-label use for body recomposition and longevity remains controversial — long-term cancer-incidence and insulin-resistance data are mixed.
S-tier — foundational compound. "Plenty of human research, substantive collagen/sleep/MPS benefits." Notes UGC (underground) HGH at $200-300/mo running 5-6 IU is achievable for committed bodybuilders; quality varies wildly. Strongly cautions against running above ~6 IU without medical supervision.
Adult GH replacement is well-established for documented deficiency (post-pituitary surgery, Sheehan syndrome, hypopituitarism). Off-label longevity / body-recomp use sits in clinical grey territory — most endocrinologists won't prescribe without IGF-1 below age-adjusted reference range. Insurance coverage is strict; cash-pay is common for off-label.
Per-claim grading. Each claim is graded independently — same peptide, different claims can carry different grades.
External links to PubMed searches, ClinicalTrials.gov, and FDA materials. We do not host papers — we point at canonical sources.
Pre-filled with this compound's published dose range: 1-4 IU · daily, subcutaneous
Calculator is a discussion tool. Verify reconstitution + dosing with a qualified provider. Stack is not a prescription source. Use sterile technique and inspect every vial.
How much a first cycle actually costs across the channels people use. Pick the protocol length you're considering — Stack multiplies the monthly band by cycle weeks. Same caveats apply: ranges are facts, quality varies, this is not legal advice.
Numbers reflect publicly-advertised price ranges, not vendor quotes. Insurance, prescription costs, and shipping aren't included. Channels marked unavailable are filtered out.
See pharmacies for this compound →Approximate monthly cost across the channels users actually consider — brand FDA-approved retail, US 503A compounding, Mexican pharmacies, MX farmacias magistrales, and the research-grey market. Stack lists ranges, not vendor names. Quality varies wildly across channels — see each band's note.
Dosing assumption: 2-4 IU daily (recreational), prescriptions for adult GH-deficiency typically 0.2-0.6 mg daily
Pfizer Genotropin, Lilly Humatrope, Sandoz Omnitrope, others. Insurance covers GHD indication. Pediatric-growth pricing higher than adult.
As of 2026-04Brand HGH available in MX with prescription, materially cheaper than US retail.
As of 2026-04Underground HGH market range — Chinese-source generics. Bodybuilder-coach commentary frequently quotes "$200-300/month for 5-6 IU daily" (Eric Janicki, 2026).
As of 2026-04FDA approved (multiple brands)