Humanin
24-amino acid mitochondrial-encoded peptide. Cytoprotective signaling against apoptosis, neurodegeneration, metabolic stress.
This compound sits in research-grey territory. The caveats below carry more weight than for FDA-approved entries — read them.
Encoded in 16S rRNA gene. First mitochondrial-derived peptide identified (2003). Humanin levels decline with age. Strong preclinical neuroprotection (Alzheimer models, stroke). Human evidence limited to observational biomarker correlations. Sister peptides MOTS-c and SHLP series form an emerging class.
No published human RCTs. All efficacy claims extrapolated from preclinical work or correlation studies.
Per-claim grading. Each claim is graded independently — same peptide, different claims can carry different grades.
- DMechanistic / anecdotal
Humanin — primary mechanism: 24-amino acid mitochondrial-encoded peptide. cytoprotective signaling against apoptosis, neurodegeneration, metabolic stress.
2 supporting referencesVerified 5d ago
External links to PubMed searches, ClinicalTrials.gov, and FDA materials. We do not host papers — we point at canonical sources.
Pre-filled with this compound's published dose range: 5-10 mg · weekly, subcutaneous
Draw volume exceeds 100 units (1 mL). Either reduce dose or split into multiple injections.
Calculator is a discussion tool. Verify reconstitution + dosing with a qualified provider. Stack is not a prescription source. Use sterile technique and inspect every vial.
Research-grey