Humanin
Monograph · DHumanin
24-amino acid mitochondrial-encoded peptide. Cytoprotective signaling against apoptosis, neurodegeneration, metabolic stress.
How it clearsHalf cleared in ~30min. Most (~96%) gone by ~2.5h.
This compound sits in research-grey territory. The caveats below carry more weight than for FDA-approved entries — read them.
Encoded in 16S rRNA gene. First mitochondrial-derived peptide identified (2003). Humanin levels decline with age. Strong preclinical neuroprotection (Alzheimer models, stroke). Human evidence limited to observational biomarker correlations. Sister peptides MOTS-c and SHLP series form an emerging class.
Early-stage — most claims are extrapolated from animal or in-vitro studies with no human replication at scale. Longevity effects specifically resist short-term human measurement, which means both positive and negative signals are genuinely difficult to read.
No published human RCTs. All efficacy claims extrapolated from preclinical work or correlation studies.
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Upload in /historyPer-claim grading. Each claim is graded independently — same peptide, different claims can carry different grades.
- DMechanistic / anecdotal
Humanin peptide fragments show cytoprotective signaling in preclinical models
1 supporting referencesVerified 23d ago
External links to PubMed searches, ClinicalTrials.gov, and FDA materials. We do not host papers — we point at canonical sources.
Pre-filled with this compound's published dose range: 5-10 mg · weekly, subcutaneous
Draw volume exceeds 100 units (1 mL). Either reduce dose or split into multiple injections.
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Handoff & sources
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