SCF (Stem Cell Factor)
Cytokine binding c-Kit receptor (CD117). Drives hematopoietic + melanocyte stem-cell activity. In skin: contributes to melanocyte homeostasis + follicular stem-cell maintenance — the mechanistic rationale for cosmetic-serum inclusion.
How it clearsHalf cleared in ~4h. Most (~96%) gone by ~20h.
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This compound sits in research-grey territory. The caveats below carry more weight than for FDA-approved entries — read them.
Recombinant SCF (ancestim) had FDA approval as Stemgen for stem-cell mobilization in cancer-treatment contexts but is no longer marketed in the US. Cosmetic-serum SCF (in Blueprint Serum + other biomimetic-peptide formulations) is included for the melanocyte + follicular stem-cell maintenance rationale. No published cosmetic-indication RCT validates topical SCF efficacy at the included concentrations.
Most niche of the Blueprint Serum biomimetic-peptide set. Mast-cell activation is a theoretical concern in topical formulations for patients with mastocytosis or severe atopy. No RCT validates the cosmetic-indication claims at the topical-serum concentrations used.
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Upload in /historyPer-claim grading. Each claim is graded independently — same peptide, different claims can carry different grades.
- DMechanistic / anecdotal
SCF (Stem Cell Factor) — primary mechanism: cytokine binding c-kit receptor (cd117). drives hematopoietic + melanocyte stem-cell activity. in skin: contributes to melanocyte homeostasis + follicular stem-cell maintenance — the mechanistic rationale for cosmetic-serum inclusion.
1 supporting referencesVerified 13d ago
External links to PubMed searches, ClinicalTrials.gov, and FDA materials. We do not host papers — we point at canonical sources.
Cosmetic-serum use legal (peptide-tier ingredient) · injectable use is research-grey
Pre-filled with this compound's published dose range: Topical: ppm-level in cosmetic serum · twice daily, topical
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