Taurine
Monograph · ATaurine
Conditionally essential sulfonic acid abundant in muscle, heart, retina, and brain. Modulates calcium signaling, mitochondrial function, osmotic regulation, and bile acid conjugation. Serum taurine declines ~80% from youth to old age.
How it clearsHalf cleared in ~1.5h. Most (~96%) gone by ~7.5h.
Compare these compounds
Mechanism, evidence, legal path, cost — all side-by-side.
Singh et al. (Science 2023) showed taurine supplementation extended healthspan ~10% in mice and worms, with some human age-reversal biomarker data. This paper drove significant community adoption. Human clinical trials are underway. Bryan Johnson's Blueprint protocol includes 2 g/day. Mechanistic pathways: mitochondrial uncoupling improvement, GABA receptor modulation (anxiolytic), and gut microbiome support.
Interesting longevity signals with mechanistic plausibility — but most human data is still in early collection. The biology is real; the human response curve isn't fully mapped yet. Users in this tier are genuinely contributing to what becomes established evidence.
Very safe at typical doses. Caution in renal failure (taurine is renally cleared). Some case reports of altered kidney function at very high doses (>40 g/day — irrelevant at longevity doses). Energy drink associations (taurine + caffeine combinations) are not applicable to standalone supplement use.
Upload your data to see how it relates to Taurine.
Upload a lab file (LabCorp / Quest) or DNA file (23andMe / AncestryDNA). Stack will show your specific markers alongside the literature-reported response windows.
Upload in /historyPer-claim grading. Each claim is graded independently — same peptide, different claims can carry different grades.
- CLimited evidence
Conditionally essential sulfonic acid abundant in muscle, heart, retina, and brain
1 supporting referencesVerified 24d ago - AStrong evidence
Taurine is an FDA-approved drug active ingredient
1 supporting referencesVerified 24d ago
External links to PubMed searches, ClinicalTrials.gov, and FDA materials. We do not host papers — we point at canonical sources.
Dietary supplement (DSHEA). GRAS as food ingredient. No FDA drug approval.
Distilled themes from named communities — Reddit threads, forums, creator commentary. Not direct quotes; not clinical evidence. Useful for calibrating expectations against what real self-experimenters report.
Post-Science 2023 paper adoption was immediate. Most users report no noticeable subjective effect at 1–2 g/day — consistent with the paper's focus on biomarkers rather than subjective outcomes. Stacked with creatine in longevity protocols.
Next visit & citations
Handoff & sources
Running this compound? Log it in /history, then open Dr Passport before your visit. Methodology explains grades; the research dashboard sorts the full catalog with citations.