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Monograph
RESEARCH GREYP-070
Longevity

Vesugen

Tripeptide (Lys-Glu-Asp) from the Khavinson cytomedin lineage. Targeted at vascular endothelium — Russian Academy work claims normalization of vascular tone + endothelial repair in aging cohorts.

ExperimentalLongevity
Typical dose10 mg subcutaneous (Khavinson protocol)
Frequencydaily × 10 days, 1-2× yearly
Half-life4h
Citations indexed12
100%50%0%04h8h12h16h20ht½ 4hPK · plasma

How it clearsHalf cleared in ~4h. Most (~96%) gone by ~20h.

DeliveryInjectable
Half-life~4h
EvidenceExperimental
Citations12
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Research grey

This compound sits in research-grey territory. The caveats below carry more weight than for FDA-approved entries — read them.

Mechanism

One of dozens of Khavinson-lab synthetic-tetrapeptide / tripeptide bioregulators (Epitalon = pineal, Pinealon = brain, Cardiogen = heart, Vesugen = vessels, Bronchogen = lung, Pancrogen = pancreas, Testagen = immune). The whole family rests on Russian-academy clinical practice + cohort observations, with essentially zero Western RCT replication. Khavinson reported 6-year + 12-year follow-up data on combined cytomedin courses in Russian gerontology journals. Adoption outside Russia is biohacker-niche.

Specifics
Cellular aging concernsLow energy / fatigue
Caveats

All efficacy evidence is Khavinson-lineage. Western replication is absent. Counterfeit + identity-verification problem for grey-market imports from Eastern Europe is severe. Don't conflate Vesugen with Pinealon, Cardiogen, etc — same lineage but different targets.

Evidence levelExperimental
Regulatory statusRussian regulatory pathway only · grey-market in US/EU · no Western RCT body
DNA / pharmacogenomicsLow — No actionable PG.
Your data · empty

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Claims & evidence

Per-claim grading. Each claim is graded independently — same peptide, different claims can carry different grades.

  • DMechanistic / anecdotal

    Vesugen — primary mechanism: tripeptide (lys-glu-asp) from the khavinson cytomedin lineage. targeted at vascular endothelium — russian academy work claims normalization of vascular tone + endothelial repair in aging cohorts.

    1 supporting referencesVerified 13d ago
References

External links to PubMed searches, ClinicalTrials.gov, and FDA materials. We do not host papers — we point at canonical sources.

  • ReviewEN
    REVIEWAcademic-fundedVerified 13d ago
    PubMed — Khavinson cytomedins gerontology
RESEARCH GREYP-070

Russian regulatory pathway only · grey-market in US/EU · no Western RCT body

Can I get it? →
Reconstitution calculatorVesugen

Pre-filled with this compound's published dose range: 10 mg subcutaneous (Khavinson protocol) · daily × 10 days, 1-2× yearly

Concentration2.50 mg/mL
Draw volume4.000 mL
Insulin syringe400.0 u
Doses per vial0
U-100 syringe — fill to indicatorU-100 · 1 mL
0u25u50u75u100u
Watch

Draw volume exceeds 100 units (1 mL). Either reduce dose or split into multiple injections.

Calculator is a discussion tool. Verify reconstitution + dosing with a qualified provider. Stack is not a prescription source. Use sterile technique and inspect every vial.

No field reports yet

Field reports are added as users share their real-world protocols.

Vesugen10 mg subcutaneous (Khavinson protocol) · daily × 10 days, 1-2× yearly

Next visit & citations

Handoff & sources

Running this compound? Log it in /history, then open Dr Passport before your visit. Methodology explains grades; the research dashboard sorts the full catalog with citations.

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Discussion guide, not prescription

stack is an exploration engine. Output is a discussion guide for a conversation with a licensed provider — never a prescription, dose recommendation, or sourcing instruction. Peptides discussed include compounds with limited human evidence and varying legal status by jurisdiction. Verify everything with a qualified clinician before any decision.

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