Cagrilintide
Monograph · BCagrilintide
Long-acting amylin analog. Activates amylin and calcitonin receptors to suppress appetite via complementary pathway to GLP-1.
How it clearsHalf cleared in ~7d. Most (~96%) gone by ~37d.
This compound sits in research-grey territory. The caveats below carry more weight than for FDA-approved entries — read them.
Novo Nordisk candidate. Combined with semaglutide as CagriSema — Phase 3 REDEFINE trials underway. Mechanism is complementary to GLP-1 (amylin signaling), so combined product targets stronger weight loss than semaglutide alone.
Emerging metabolic evidence with a real mechanistic basis — but the dose-response curve is wider than in established compounds. The first 3–4 weeks should be treated as response-threshold discovery, not outcome measurement. Individual variation here is a feature of the tier, not a flaw in the compound.
Not approved. Standalone use outside the CagriSema trial protocol is research-only. Identity verification of grey-market product is poor.
Disulfide bridge between Cys2-Cys7. C20 fatty acid conjugated at K1 via γGlu spacer.
Upload your data to see how it relates to Cagrilintide.
Upload a lab file (LabCorp / Quest) or DNA file (23andMe / AncestryDNA). Stack will show your specific markers alongside the literature-reported response windows.
Upload in /historyPer-claim grading. Each claim is graded independently — same peptide, different claims can carry different grades.
- BModerate evidence
Cagrilintide + semaglutide combinations show additive weight loss in trials
1 supporting referencesVerified 23d ago
External links to PubMed searches, ClinicalTrials.gov, and FDA materials. We do not host papers — we point at canonical sources.
Pre-filled with this compound's published dose range: 0.16-2.4 mg · weekly, subcutaneous (trial protocols)
Calculator is a discussion tool. Verify reconstitution + dosing with a qualified provider. Stack is not a prescription source. Use sterile technique and inspect every vial.
No field reports yet
Field reports are added as users share their real-world protocols.
Next visit & citations
Handoff & sources
Running this compound? Log it in /history, then open Dr Passport before your visit. Methodology explains grades; the research dashboard sorts the full catalog with citations.