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Monograph
PENDING · FEB 2027P-026
Hormones

GHRP-6

Six-amino acid ghrelin agonist. Notable for pronounced hunger stimulation in addition to GH release.

EmergingHormones
Typical dose100-200 µg
Frequency2-3x daily, subcutaneous
Half-life0.5h
Citations indexed28
DeliveryInjectable
Half-life~30min
EvidenceEmerging
Citations28
Synergy checkCompareReconstitution calc
Mechanism

Older GHRP class. Stronger appetite signal makes it useful for cachexia models but problematic for body-composition users. Largely superseded by ipamorelin in modern stacks.

Specifics
Body composition (lean mass)
Caveats

Hunger stimulation can backfire for fat-loss goals. Modern alternatives (ipamorelin) are usually preferred.

sequence · 6 aa
HXAWXK

His-D-Trp-Ala-Trp-D-Phe-Lys-NH₂ (6 aa with D-stereoisomers).

Evidence levelEmerging
Regulatory statusExpected reclassification — PCAC review Feb 2027
DNA / pharmacogenomicsModerate — GHSR variants relevant.
Pairs & ConflictsCheck full stack →
Redundant with

Same mechanism class — adds cost without adding signal.

CJC / IPAGHRP-2HexarelinMK-677
Claims & evidence

Per-claim grading. Each claim is graded independently — same peptide, different claims can carry different grades.

  • CLimited evidence

    GHRP-6 — primary mechanism: six-amino acid ghrelin agonist. notable for pronounced hunger stimulation in addition to gh release.

    1 supporting referencesVerified 5d ago
References

External links to PubMed searches, ClinicalTrials.gov, and FDA materials. We do not host papers — we point at canonical sources.

  • PubMedEN
    REVIEWFunding undisclosedVerified 5d ago
    PubMed — GHRP-6
Reconstitution calculatorGHRP-6

Pre-filled with this compound's published dose range: 100-200 µg · 2-3x daily, subcutaneous

Concentration2.50 mg/mL
Draw volume0.060 mL
Insulin syringe6.0 u
Doses per vial33
U-100 syringe — fill to indicatorU-100 · 1 mL
0u25u50u75u100u

Calculator is a discussion tool. Verify reconstitution + dosing with a qualified provider. Stack is not a prescription source. Use sterile technique and inspect every vial.

PENDING · FEB 2027P-026

Expected reclassification — PCAC review Feb 2027

Feb 15, 2027USScheduled reviewUpcoming

PCAC review · February 2027 panel

FDA's Pharmacy Compounding Advisory Committee scheduled to review the second cohort of peptides removed from Category 2 in April 2026. Panel votes whether to add each to the official 503A bulks list.

GHRP-6100-200 µg · 2-3x daily, subcutaneous
Discussion guide, not prescription

stack is an exploration engine. Output is a discussion guide for a conversation with a licensed provider — never a prescription, dose recommendation, or sourcing instruction. Peptides discussed include compounds with limited human evidence and varying legal status by jurisdiction. Verify everything with a qualified clinician before any decision.

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