Selank is a heptapeptide derivative of tuftsin developed at the Russian Academy of Medical Sciences in the 1990s. Russian-language clinical literature documents anxiolytic effect without sedation or dependence. Western RCT replication is absent; the 'no dependence' claim for an anxiolytic is extraordinary and remains unverified outside Russian-academy lineage.
Selank
Synthetic analog of tuftsin. Anxiolytic without sedation; modulates GABAergic and serotonergic tone.
This compound sits in research-grey territory. The caveats below carry more weight than for FDA-approved entries — read them.
Thr-Lys-Pro-Arg-Pro-Gly-Pro. Developed alongside Semax. Modulates enkephalin metabolism and GABA-A receptor function. Russian clinical trials report anxiolytic effects without sedation, dependence, or withdrawal — a profile that is unusual if it replicates. Western RCTs are absent.
All efficacy literature from one Russian institute lineage. Counterfeit risk for nasal sprays. Anxiolytic without sedation/dependence is an extraordinary claim — treat skeptically until Western replication.
Stack doesn't rank peptides — we surface the diversity of opinion. Each card paraphrases a public-record stance from a named source. Where they conflict is where you should slow down and read both.
Outside Russian-language sources, Selank has near-zero registered clinical trials. The 'anxiolytic without GABAergic side effects' mechanism is plausible but uncorroborated by Western trials. PCAC nomination was withdrawn in April 2026 (separate procedural path from Semax).
Per-claim grading. Each claim is graded independently — same peptide, different claims can carry different grades.
- CLimited evidence
Selank shows anxiolytic effect in Russian clinical literature, comparable in profile to medazepam without sedation
1 supporting referencesVerified 5d ago
External links to PubMed searches, ClinicalTrials.gov, and FDA materials. We do not host papers — we point at canonical sources.
Pre-filled with this compound's published dose range: 250-750 µg · daily, intranasal
Calculator is a discussion tool. Verify reconstitution + dosing with a qualified provider. Stack is not a prescription source. Use sterile technique and inspect every vial.
How much a first cycle actually costs across the channels people use. Pick the protocol length you're considering — Stack multiplies the monthly band by cycle weeks. Same caveats apply: ranges are facts, quality varies, this is not legal advice.
Numbers reflect publicly-advertised price ranges, not vendor quotes. Insurance, prescription costs, and shipping aren't included. Channels marked unavailable are filtered out.
See pharmacies for this compound →Approximate monthly cost across the channels users actually consider — brand FDA-approved retail, US 503A compounding, Mexican pharmacies, MX farmacias magistrales, and the research-grey market. Stack lists ranges, not vendor names. Quality varies wildly across channels — see each band's note.
Same Russian-source channel as Semax. Selank's PCAC nomination was withdrawn April 2026 — separate procedural path.
As of 2026-04Public-source attribution across the production + distribution chain. Stack does not endorse vendors — this is who is in the chain, not which one is best.
Selank(Various Russian manufacturers)
RUAnxiolytic (Russian regulatory, not FDA)
Source: Russian regulatory anxiolytic peptideVerified 5d ago
Peptide Partners
Research3rd-party COA per batchFinnrick ✓US · CA · AU · UKOne of the most consistently recommended vendors on r/Peptides since the Peptide Sciences shutdown (March 2026). Third-party COA published per batch. HPLC purity ≥99%.
For laboratory use only / not for human consumption. Stack may earn affiliate commissions.
Paradigm Peptide
Research3rd-party COA per batchFinnrick ✓US · CALong-established US vendor (7+ years). Broad catalog including GHRPs, GHRHs, and cognitive peptides. Third-party HPLC and mass-spec COA per batch. Active Finnrick Analytics coverage.
For laboratory use only / not for human consumption. Stack may earn affiliate commissions.
Orbitrex Peptides
Research3rd-party COA per batchUSNewer vendor with fast turnaround and competitive pricing. Third-party COA on all products. Building Finnrick coverage. Frequently recommended post-Peptide Sciences shutdown.
For laboratory use only / not for human consumption. Stack may earn affiliate commissions.
XL Peptides
Research3rd-party COA per batchFinnrick ✓US · CA · AUKnown for above-average catalog depth, including harder-to-find compounds (SS-31, humanin, Foxo4-DRI). Third-party HPLC published. Active Finnrick coverage.
For laboratory use only / not for human consumption. Stack may earn affiliate commissions.
Cosmic Nootropics
Specialty Import3rd-party COA on requestUS · EU · AU · CAPrimary EU-based importer for Russian-manufactured cognitive peptides: Semax, Selank, Cortexin, Cerebrolysin, Pinealon, Epitalon. Pharmaceutical-grade Russian-made products. COA from Russian manufacturers.
For laboratory use only / not for human consumption. Stack may earn affiliate commissions.
Compounding nomination withdrawn Apr 2026 — distinct from peptides under PCAC review
Selank nomination withdrawn from PCAC docket
Selank's nomination for 503A bulks list inclusion was withdrawn before the PCAC panel scheduled it. Selank now follows a separate procedural path — likely requires fresh evidence submission.
FDA places peptides on Category 2 'significant safety concerns' list
FDA's Pharmacy Compounding Advisory Committee categorized a wide list of peptides as Category 2 ('significant safety concerns'), effectively banning their compounding at 503A and 503B pharmacies. Affected: BPC-157, TB-500, Epitalon, GHK-Cu, MOTS-c, DSIP, Dihexa, MK-677, Melanotan II, KPV, Semax, Selank, LL-37 and others.