Kisspeptin
Monograph · B10-amino acid C-terminal fragment of KISS1 gene product. Master regulator upstream of GnRH — stimulates LH/FSH release with high physiological precision.
How it clearsHalf cleared in ~30min. Most (~96%) gone by ~2.5h.
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Mechanism, evidence, legal path, cost — all side-by-side.
Imperial College London (Dhillo lab) clinical research uses kisspeptin in hypothalamic amenorrhea and IVF cycle optimization. Pulsatile delivery mimics endogenous GnRH biology better than HCG. Not commercialized; clinical access is research-protocol-only.
Emerging hormonal signal with real mechanistic basis — but this is where subjective monitoring most consistently misleads. Hormonal shifts at this tier are often lab-detectable before they become subjectively felt. Without bloodwork at 6–8 weeks, you are tracking the wrong signal.
Not commercially available. Anything sold as 'kisspeptin' to retail biohackers should be treated with extreme skepticism. Real protocols use IV pulse infusions, not subcutaneous self-administration.
Upload a lab file (LabCorp / Quest) or DNA file (23andMe / AncestryDNA). Stack will show your specific markers alongside the literature-reported response windows.
Upload in /historyPer-claim grading. Each claim is graded independently — same peptide, different claims can carry different grades.
External links to PubMed searches, ClinicalTrials.gov, and FDA materials. We do not host papers — we point at canonical sources.
Expected reclassification — PCAC review Feb 2027
FDA's Pharmacy Compounding Advisory Committee scheduled to review the second cohort of peptides removed from Category 2 in April 2026. Panel votes whether to add each to the official 503A bulks list.
Pre-filled with this compound's published dose range: research-only · research-protocol IV pulses
Calculator is a discussion tool. Verify reconstitution + dosing with a qualified provider. Stack is not a prescription source. Use sterile technique and inspect every vial.
How much a first cycle actually costs across the channels people use. Pick the protocol length you're considering — Stack multiplies the monthly band by cycle weeks. Same caveats apply: ranges are facts, quality varies, this is not legal advice.
Numbers reflect publicly-advertised price ranges, not vendor quotes. Insurance, prescription costs, and shipping aren't included. Channels marked unavailable are filtered out.
See pharmacies for this compound →Approximate monthly cost across the channels users actually consider — brand FDA-approved retail, US 503A compounding, Mexican pharmacies, MX farmacias magistrales, and the research-grey market. Stack lists ranges, not vendor names. Quality varies wildly across channels — see each band's note.
Dosing assumption: 50-100 µg/day subcutaneous (kisspeptin-10 fragment)
Research-grey only. Imperial College London (Dhillo lab) has the leading clinical human evidence; community use is way ahead of that pipeline. On the Feb 2027 PCAC docket.
As of 2026-04No field reports yet
Field reports are added as users share their real-world protocols.
Next visit & citations
Running this compound? Log it in /history, then open Dr Passport before your visit. Methodology explains grades; the research dashboard sorts the full catalog with citations.