Exenatide
Monograph · AExenatide
Synthetic version of exendin-4 from Gila monster saliva. First-in-class GLP-1 receptor agonist (twice-daily Byetta and weekly Bydureon).
How it clearsHalf cleared in ~7d. Most (~96%) gone by ~35d.
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FDA-approved 2005 (Byetta) and 2012 (Bydureon). Pioneered the GLP-1 class. Less weight-loss potency than later analogs but well-characterized 20-year safety record.
Cohort curves show movement — your n=1 often lags the median by one check-in cycle. The gap between "I should feel it" and "labs show it" is where most people quit early. Metabolic compounds still need lifestyle structure; modest results without it are mechanism, not failure.
Older class member; rarely first-line in 2025. Twice-daily Byetta has injection-burden compliance issues. Same class watches.
Known risk or pharmacological conflict.
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Upload in /historyPer-claim grading. Each claim is graded independently — same peptide, different claims can carry different grades.
- AStrong evidence
Exenatide lowers HbA1c in type 2 diabetes RCTs
1 supporting referencesVerified 23d ago
External links to PubMed searches, ClinicalTrials.gov, and FDA materials. We do not host papers — we point at canonical sources.
Pre-filled with this compound's published dose range: 5-10 µg twice daily or 2 mg weekly · varies by formulation, subcutaneous
Draw volume is below 5 units — hard to measure accurately on most syringes. Consider adding more BAC water to dilute, or moving to a smaller syringe.
Calculator is a discussion tool. Verify reconstitution + dosing with a qualified provider. Stack is not a prescription source. Use sterile technique and inspect every vial.
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